Engineering antibody and T cell receptor fragments : from specificity design to optimization of stability and affinity

B and T cells comprise the two major arms of the adaptive immune response tasked with clearing and preventing infection; molecular recognition in these cells occurs through antibodies and T cell receptors (TCRs), respectively. Highly successful therapeutics, clinical diagnostics and laboratory tools...

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Bibliographic Details
Main Author: Entzminger, Kevin Clifford
Format: Others
Language:en
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/2152/28321