The segregation of native and foreign extra-chromosomal genetic elements in Saccharomyces cerevisiae : stable propagation by hitchhiking on chromosomes
The 2 micron plasmid of the budding yeast Saccharomyces cerevisiae resides in the nucleus as an extra-chromosomal element with a steady state copy number around 40-60 per cell. As a benign but selfish DNA element, the plasmid utilizes a self-coded partitioning system and an amplification system to e...
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Format: | Others |
Language: | en_US |
Published: |
2013
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Online Access: | http://hdl.handle.net/2152/22068 |