Bi-directional signaling between melanoma and the microenvironment generates a protective niche that mediates therapeutic escape
Very few cancer patients are cured through drug therapy alone, with the majority exhibiting acquired resistance. To date, most studies of therapeutic escape have focused upon tumor-intrinsic mechanisms of drug resistance with little attention paid to the role of normal host cells in preventing compl...
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| Format: | Others |
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Scholar Commons
2014
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| Online Access: | https://scholarcommons.usf.edu/etd/5215 https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=6411&context=etd |