Matrix Metalloproteinase genes are transcriptionally regulated by E2F transcription factors: a link between cell cycle control and metastatic progression

The RbµE2F transcriptional regulatory pathway plays a critical role in the cell cycle. Rb is inactivated through multiple waves of phosphorylation, mediated mainly by cyclin D and cyclin E associated kinases. Once Rb is inactivated, cells can enter Sµphase. Collectively, three Rb family members and...

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Bibliographic Details
Main Author: Johnson, Jacqueline Lea
Format: Others
Published: Scholar Commons 2012
Subjects:
E2F
Online Access:http://scholarcommons.usf.edu/etd/4092
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=5288&context=etd