New Peptide-pair Screening Strategy and Peptidylglycine a-Hydroxylating Monooxygenase (PHM) Based Enrichment Method for the Discovery of Novel a-Amidated Peptides
Peptide a-amidation is known as a signature of bioactivity due to the fact that half of the bioactive peptides found in the nervous and endocrine systems are a-amidated and that most known a-amidated peptides are bioactive. a-Amidated peptides are produced by the oxidative cleavage of glycine-extend...
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| Format: | Others |
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Scholar Commons
2010
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| Online Access: | http://scholarcommons.usf.edu/etd/3580 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=4744&context=etd |