Investigation of the effects of increased levels of O-GlcNAc protein modification on protein kinase C and Akt

O-linked N-acetylglucosamine (O-GlcNAc) is an abundant and ubiquitous post-translational modification that has been shown to play a role in regulating a variety of intracellular processes. The pathway responsible for generating the O-GlcNAc modification, the hexosamine biosynthetic pathway (HBP), ha...

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Bibliographic Details
Main Author: Matthews, Jason Aaron
Format: Others
Published: Scholar Commons 2006
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/2618
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3617&context=etd