N-Thiolated b-lactam antibiotics: Synthesis and structure-activity studies of C3 oxygenated derivatives and attachement to new, functionalized caprolactone monomers and polymers

N-Thiolated beta-lactams are a new class of anti-MRSA and anti-Bacillus agents that have recently been reported by our laboratories. From previous studies performed in our laboratories, it is believed that the N-thiolated beta-lactams exert their antimicrobial activity through a unique mode of actio...

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Bibliographic Details
Main Author: Leslie, J Michelle
Format: Others
Published: Scholar Commons 2006
Subjects:
Online Access:http://scholarcommons.usf.edu/etd/2601
http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3600&context=etd