The Rad9-Rad1-Hus1 complex and Bif-1 regulate multiple mechanisms that affect sensitivity to DNA damage
The resistance of cancer cells to traditional chemotherapeutic agents is a major obstacle in the successful treatment of cancer. Cancer cells manipulate a variety of signaling pathways to enhance resistance to anticancer agents; such mechanisms include disrupting the DNA damage response and hyperact...
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Scholar Commons
2009
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Online Access: | http://scholarcommons.usf.edu/etd/2102 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=3101&context=etd |