On the Involvement of the Low-Density Lipoprotein Receptor in the Pathogenesis and Progression of Alzheimer’s Disease

Alzheimer's disease (AD) is the most prevalent form of age-associated dementia. Cholesterol dysregulation is linked with AD onset. Besides age, the most important risk factor associated with AD is the inheritance of the epsilon-4 allele of apolipoprotein E, a cholesterol transporter. In additio...

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Bibliographic Details
Main Author: Abisambra Socarras, Jose Francisco
Format: Others
Published: Scholar Commons 2009
Subjects:
Online Access:https://scholarcommons.usf.edu/etd/1554
https://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=2553&context=etd