Application of PI-deconvolution to the screening of protein ligand combinatorial libraries using the yeast-two-hybrid assay

Reagents that bind proteins are applicable in biology for detection of molecules, perturbation of signaling pathways and development of small-molecule pharmaceuticals. Protein ligands interact with proteins, inhibiting or altering their function. They are isolated from combinatorial libraries to int...

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Bibliographic Details
Main Author: Aparicio de Navaraez, Alberto
Other Authors: Geyer, Ron
Format: Others
Language:en
Published: University of Saskatchewan 2008
Subjects:
Online Access:http://library.usask.ca/theses/available/etd-11242008-141444/