Bcl-xL/xS phosphorylation regulates the sensitivity of PC12 cells to apoptosis
The Bcl-2 family of proteins contains both anti-apoptotic (e.g.Bcl-2, Bcl-xL) and pro-apoptotic (e.g.Bad, Bcl-xS) proteins. The Bcl-xL and Bcl-xS are splice variants, but have different functions during apoptosis. The pro-survival kinase Akt can phosphorylate certain Bcl-2-related proteins, specific...
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| Format: | Others |
| Language: | en |
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University of Saskatchewan
2010
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| Online Access: | http://library.usask.ca/theses/available/etd-01112010-143311/ |