Evasion and Attack: Structural Studies of a Bacterial Albumin-binding Protein and of a Cephalosporin Biosynthetic Enzyme

Evasion and Attack: Structural Studies of a Bacterial Albumin-binding Protein and of a Cephalosporin Biosynthetic Enzyme

This thesis describes the crystal structures of two proteins in the context of combatting bacterial infections. The GA module is a bacterial albumin-binding domain from a surface protein expressed by pathogenic strains of the human commensal bacterium Finegoldia magna. The structure of the GA module...

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Bibliographic Details
Main Author: Lejon, Sara
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för cell- och molekylärbiologi 2008
Subjects:
human serum albumin
GA module
albumin-binding
Finegoldia magna
deacetylcephalosporin C acetyltransferase
cephalosporin C
antibiotic
beta-lactam
biosynthesis
Acremonium chrysogenum
X-ray crystallography
Structural biology
Strukturbiologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8399
http://nbn-resolving.de/urn:isbn:978-91-554-7062-3

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8399
http://nbn-resolving.de/urn:isbn:978-91-554-7062-3

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