Liquid Chromatography-Mass Spectrometry as a Tool for Drug Metabolite Identification in Biological Fluids : With Application to Ketobemidone

Liquid Chromatography-Mass Spectrometry as a Tool for Drug Metabolite Identification in Biological Fluids : With Application to Ketobemidone

Electrospray ionization (ESI) mass spectrometry (MS) in combination with liquid chromatography (LC) is an excellent tool for the identification of drug metabolites. Utilizing this hyphenated technique in combination with proper sample pretreatment, the metabolic pathways of the analgesic drug ketobe...

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Bibliographic Details
Main Author: Sundström, Ingela
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Avdelningen för analytisk farmaceutisk kemi 2007
Subjects:
Analytical chemistry
LC-MS/MS
accurate mass measurement
drug metabolites
microdialysate
brain
fluorinated stationary phase
phenylboronic acid
retention mechanism
Analytisk kemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7909
http://nbn-resolving.de/urn:isbn:978-91-554-6908-5

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7909
http://nbn-resolving.de/urn:isbn:978-91-554-6908-5

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