DNA Tools and Microfluidic Systems for Molecular Analysis

DNA Tools and Microfluidic Systems for Molecular Analysis

Improved methods are needed to interrogate the genome and the proteome. Methods with high selectivity, wide dynamic range, and excellent precision, capable of simultaneously analyzing many biomolecules are required to decipher cellular function. This thesis describes a molecular and microfluidic too...

Full description

Bibliographic Details
Main Author:	Jarvius, Jonas
Format:	Doctoral Thesis
Language:	English
Published:	Uppsala universitet, Institutionen för genetik och patologi 2006
Subjects:	Molecular medicine Proximity ligation Microfluidics Single molecule detection Microarray Bonding Molekylärmedicin
Online Access:	http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7079 http://nbn-resolving.de/urn:isbn:91-554-6616-8

Similar Items

Biomolecular Analysis by Dual-Tag Microarrays and Single Molecule Amplification
by: Ericsson, Olle
Published: (2008)

Proximity Ligation : Transforming protein analysis into nucleic acid detection through proximity-dependent ligation of DNA sequence tagged protein-binders
by: Fredriksson, Simon
Published: (2002)

Application of proximity Ligation for Detection of Proteins, Biomolecular Interactions, and Single Copies of Pathogens
by: Gustafsdottir, Sigrun Margret
Published: (2006)

Development and Application of Triple Specific Proximity Ligation Assays (3PLA)
by: Schallmeiner, Edith
Published: (2007)

Proximity Ligation as a Universal Protein Detection Tool
by: Gullberg, Mats
Published: (2003)

Functional Genomics of Bone Metabolism : Novel Candidate Genes Identified by Studies in Chicken Models
by: Rubin, Carl-Johan
Published: (2008)

Microarray Technology for Genotyping in Pharmacogenetics
by: Liljedahl, Ulrika
Published: (2004)

Using Minisequencing Technology for Analysing Genetic Variation in DNA and RNA
by: Fredriksson, Mona
Published: (2005)

Microfluidics for Single Molecule Detection and Material Processing
by: Hong, Sung Min
Published: (2012)

Methods for Analysis of Disease Associated Genomic Sequence Variation
by: Lovmar, Lovisa
Published: (2004)

Integrating Solid-State Nanopore Sensors within Various Microfluidic Arrays for Single-Molecule Detection
by: Tahvildari, Radin
Published: (2017)

Detection and Sequencing of Amplified Single Molecules
by: Ke, Rongqin
Published: (2012)

Inflammatory mediators in perinatal infections
by: Døllner, Henrik
Published: (2002)

Antibody Mediated Radionuclide Targeting of HER-2 for Cancer Diagnostics and Therapy : Preclinical Studies
by: Persson, Mikael
Published: (2006)

Large-Scale Genotyping for Analysis of the Type I Interferon System in Autoimmune Diseases
by: Sigurdsson, Snaevar
Published: (2006)

A Finite Element Study of the DNA Hybridization Kinetics on the Surface of Microfluidic Devices
by: Pascault, Jean-Roland Eric
Published: (2007)

Genetic Analyses using Rolling Circle or PCR Amplified Padlock Probes
by: Banér, Johan
Published: (2003)

Development of microfluidic device for high content analysis of circulating tumor cells
by: Tulukcuoglu Güneri, Ezgi
Published: (2016)

Proximity Ligation Assays for Disease Biomarkers Analysis
by: Nong, Rachel Yuan
Published: (2011)

Microfluidic and Molecular Tools for Genetic Analyses
by: Johansson, Henrik
Published: (2010)

On CD4+ T Lymphocytes in Solid Tumours
by: Marits, Per
Published: (2007)

Targeted Therapy of Colorectal Cancer : Preclinical Evaluation of a Radiolabelled Antibody
by: Almqvist, Ylva
Published: (2008)

Molecular Dynamics Simulation on the Effect of Bonding Pressure on Thermal Bonding of Polymer Microfluidic Chip
by: Mingyong Zhou, et al.
Published: (2019-03-01)

The Application of Microfluidic Technologies in Aptamer Selection
by: Yang Liu, et al.
Published: (2021-09-01)

High Content Analysis of Proteins and Protein Interactions by Proximity Ligation
by: Leuchowius, Karl-Johan
Published: (2010)

Visualizing Interacting Biomolecules In Situ
by: Weibrecht, Irene
Published: (2011)

Autoantigens in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis
by: Ardesjö, Brita
Published: (2008)

Development of Enhanced Molecular Diagnostic Tools for Protein Detection and Analysis
by: Ebai, Tonge
Published: (2017)

Visualization of Protein Activity Status in situ Using Proximity Ligation Assays
by: Jarvius, Malin
Published: (2010)

Detecting single-particle insulating collisions in microfluidics as a function of flow rate
by: Nettleton, Elizabeth Grace
Published: (2013)

Angiogenic growth factors : mechanism of action and function in vascular development
by: Rolny, Charlotte
Published: (2003)

Recent Advances in Droplet-based Microfluidic Technologies for Biochemistry and Molecular Biology
by: Joel Sánchez Barea, et al.
Published: (2019-06-01)

Microfluidic tools for molecular analysis and engineering
by: Murphy, Travis Wilson
Published: (2019)

Investigation of Polymer Flooding for Enhanced Oil Recovery using Fluorescence Microscopy and Microfluidic Devices
by: Sugar, Antonia
Published: (2021)

Tissue Factor and CD40 Ligand : Markers for the Interplay of Coagulation and Inflammation in the Acute Coronary Syndrome
by: Mälarstig, Anders
Published: (2006)

Enhancing Single Molecule Imaging in Optofluidics and Microfluidics
by: Andreas E. Vasdekis, et al.
Published: (2011-08-01)

VEGFR-2 in Endothelial Differentiation and Vascular Organization
by: Edholm, Dan
Published: (2008)

Protein Microarrays with Novel Microfluidic Methods: Current Advances
by: Chandra K. Dixit, et al.
Published: (2014-07-01)

A rapid microfluidic platform with real-time fluorescence detection system for molecular diagnosis
by: Zhigang Li, et al.
Published: (2019-01-01)

Design of a Microfluidic Based Lab-on-a-chip for Integrated Sample Manipulation and Dispensing
by: Ahamed, Mohammed Jalal
Published: (2012)