Methods for Preclinical Evaluation of Cytotoxic Drugs : With Special Reference to the Cyanoguanidine CHS 828 and Hollow Fiber Method

Methods for Preclinical Evaluation of Cytotoxic Drugs : With Special Reference to the Cyanoguanidine CHS 828 and Hollow Fiber Method

The novel cyanoguanidine CHS 828 has shown promising antitumor activity in many in vitro and in vivo studies. The long-term 14 days in vitro hollow fiber cultures, where tumor cells from different tumor cell lines were cultured inside semipermeable fibers, were more resistant to CHS 828 and other c...

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Bibliographic Details
Main Author: Hassan, Saadia Bashir
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinska vetenskaper 2004
Subjects:
Pharmacology
CHS 828
in vitro
in vivo
hollow fiber
models
NF-kB
Farmakologi
Pharmacological research
Farmakologisk forskning
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4696
http://nbn-resolving.de/urn:isbn:91-554-6113-1

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4696
http://nbn-resolving.de/urn:isbn:91-554-6113-1

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