Container closure integritytesting with High Voltage LeakDetection
There are various methods that can be used for Container Closure Integrity Testing (CCIT).Each method has its pros and cons.The choice of the CCIT-method depends on various factors such as the material of the primary packaging and product properties. High Voltage Leak Detection(HVLD) is an effective...
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| Format: | Others |
| Language: | English |
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Uppsala universitet, Nanoteknologi och funktionella material
2021
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-439566 |
| Summary: | There are various methods that can be used for Container Closure Integrity Testing (CCIT).Each method has its pros and cons.The choice of the CCIT-method depends on various factors such as the material of the primary packaging and product properties. High Voltage Leak Detection(HVLD) is an effective method. The sensitivity of the method is quite high but its is unclear whether it can detect all the hole sizes that may entails a risk for microbial contamination. The theoretical calculations and practical experiments shows that HVLD can detect holes in different positions and it can detect holes that are a few micrometers. If HVLD detect hole size that are 5 micrometers, it means that alla sizes that can make risk for microbial contamination for productsmanufacturedonAstraZeneca PET BFS can be detected with HVLD. |
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