Non-Steroidal Anti-Inflammatory Drugs in Cyclooxygenases 1 and 2 : Binding modes and mechanisms from computational methods and free energy calculations
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of drugs. They target the cyclooxygenases (COX) 1 and 2 to reduce the physiological responses of pain, fever, and inflammation. Due to their role in inducing angiogenesis, COX proteins have also been identified...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Beräkningsbiologi och bioinformatik
2017
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-328478 http://nbn-resolving.de/urn:isbn:978-91-513-0073-3 |