Improved Methods for Pharmacometric Model-Based Decision-Making in Clinical Drug Development
Pharmacometric model-based analysis using nonlinear mixed-effects models (NLMEM) has to date mainly been applied to learning activities in drug development. However, such analyses can also serve as the primary analysis in confirmatory studies, which is expected to bring higher power than traditional...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2016
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-305697 http://nbn-resolving.de/urn:isbn:978-91-554-9734-7 |