Pharmacometric Models to Improve Treatment of Tuberculosis

Pharmacometric Models to Improve Treatment of Tuberculosis

Tuberculosis (TB) is the world’s most deadly infectious disease and causes enormous public health problems. The comorbidity with HIV and the rise of multidrug-resistant TB strains impede successful therapy through drug-drug interactions and the lack of efficient second-line treatments. The aim of th...

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Bibliographic Details
Main Author: Svensson, Elin M
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2016
Subjects:
pharmacokinetics
pharmacodynamics
population approach
nonlinear mixed-effects models
multidrug-resistant tuberculosis
bedaquiline
antiretroviral
drug-drug interactions
time-to-event
albumin
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-282139
http://nbn-resolving.de/urn:isbn:978-91-554-9539-8

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