Design and Synthesis of Acyclic and Macrocyclic Peptidomimetics as Inhibitors of the Hepatitis C Virus NS3 Protease
Hepatitis C is a blood-borne disease affecting 130-170 million people worldwide. The causative agent, hepatitis C virus (HCV), infects the liver and is the major reason for chronic liver disease worldwide. The HCV NS3 protease, a key enzyme in the virus replication cycle, has been confirmed to be an...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Avdelningen för organisk farmaceutisk kemi
2012
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-163361 http://nbn-resolving.de/urn:isbn:978-91-554-8243-5 |