Insulin secretion and ASNA-1-dependent function of the endoplasmic reticulum in C. elegans
ASNA1 is a well-conserved ATPase involved in a wide range of functions, including cisplatin resistance, growth control, insulin secretion and targeting of tail-anchored (TA) proteins to membranes. It is a positive regulator of insulin secretion both in the roundworm Caenorhabditis elegans and in hum...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Kirurgi
2014
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-85906 http://nbn-resolving.de/urn:isbn:978-91-7601-004-4 |