Effects of Francisella tularensis infection on macrophage intracellular signaling

Microbes contain a number of structural components, also known as pathogen associated molecular patterns (PAMP), which can be recognized by the host defense system. The PAMP serve as ligands for Toll-like receptors (TLR) expressed on phagocytic cells. Binding of PAMP to TLR leads to activation of a...

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Bibliographic Details
Main Author: Telepnev, Maxim
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Klinisk bakteriologi 2005
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-547
http://nbn-resolving.de/urn:isbn:91-7305-898-3