Effects of Francisella tularensis infection on macrophage intracellular signaling
Microbes contain a number of structural components, also known as pathogen associated molecular patterns (PAMP), which can be recognized by the host defense system. The PAMP serve as ligands for Toll-like receptors (TLR) expressed on phagocytic cells. Binding of PAMP to TLR leads to activation of a...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Klinisk bakteriologi
2005
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-547 http://nbn-resolving.de/urn:isbn:91-7305-898-3 |