Transthyretin from a structural perspective
Conformational changes in human proteins can induce several types of diseases. The nature of the conformational changes is largely unknown, but some lead to amyloid fibril formation. Amyloid fibrils accumulate in the extra-cellular space of tissues resulting in disruption of organ function. Transthy...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Umeå centrum för molekylär patogenes (UCMP)
2004
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190 http://nbn-resolving.de/urn:isbn:91-7305-593-X |