Targeting Gb3 and apoptosis-related proteins to overcome cisplatin resistance

Background Cisplatin is used for treatment of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) but treatment with cisplatin often leads to acquired resistance to cisplatin, resulting in poor patient survival. Globotriaosylceramide (Gb3) and multidrug resistance protein 1 (...

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Bibliographic Details
Main Author: Tyler, Andreas
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Klinisk kemi 2016
Subjects:
gb3
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-119778
http://nbn-resolving.de/urn:isbn:978-91-7601-475-2

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