Targeting Gb3 and apoptosis-related proteins to overcome cisplatin resistance
Background Cisplatin is used for treatment of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) but treatment with cisplatin often leads to acquired resistance to cisplatin, resulting in poor patient survival. Globotriaosylceramide (Gb3) and multidrug resistance protein 1 (...
Main Author: | Tyler, Andreas |
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Format: | Doctoral Thesis |
Language: | English |
Published: |
Umeå universitet, Klinisk kemi
2016
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Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-119778 http://nbn-resolving.de/urn:isbn:978-91-7601-475-2 |
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