Processing of the APP family by the α-secretases ADAM10 and TACE

Alzheimer’s disease (AD) is a progressive neurodegenerative disease, which is characterized by formation of amyloid plaques in the brain. The major constituent of these plaques is the hydrophobic peptide Aβ. Aβ accumulation is considered to be the main cause of the pathology seen in AD brains. Aβ is...

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Bibliographic Details
Main Author: Jacobsen, Kristin
Format: Others
Language:English
Published: Stockholms universitet, Institutionen för neurokemi 2010
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-41996
http://nbn-resolving.de/urn:isbn:978-91-7447-000-0