Processing of the APP family by the α-secretases ADAM10 and TACE
Alzheimer’s disease (AD) is a progressive neurodegenerative disease, which is characterized by formation of amyloid plaques in the brain. The major constituent of these plaques is the hydrophobic peptide Aβ. Aβ accumulation is considered to be the main cause of the pathology seen in AD brains. Aβ is...
Main Author: | |
---|---|
Format: | Others |
Language: | English |
Published: |
Stockholms universitet, Institutionen för neurokemi
2010
|
Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-41996 http://nbn-resolving.de/urn:isbn:978-91-7447-000-0 |