Folding of the Ribosomal protein S6 : The role of sequence connectivity, overlapping foldons, and parallel pathways

Folding of the Ribosomal protein S6 : The role of sequence connectivity, overlapping foldons, and parallel pathways

To investigate how protein folding is affected by sequence connectivity five topological variants of the ribosomal protein S6 were constructed through circular permutation.  In these constructs, the chain connectivity (i.e. the order of secondary-structure elements) is changed without changing the n...

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Bibliographic Details
Main Author: Haglund, Ellinor
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för biokemi och biofysik 2009
Subjects:
protein folding
protein stability
two-state folding
S6
chevron plot
transition state
parallell pathways
foldon
two-channel landscape
protein engineering
H/D-exchange
Biochemistry
Biokemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-29963
http://nbn-resolving.de/urn:isbn:978-91-7155-939-5

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-29963
http://nbn-resolving.de/urn:isbn:978-91-7155-939-5

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