Development of an adductomic approach to identify electrophiles in vivo through their hemoglobin adducts

Humans are exposed to electrophilically reactive compounds, both formed endogenously and from exogenous exposure. Such compounds could react and form stable reaction products, adducts, at nucleophilic sites in proteins and DNA. The formation of adducts constitutes a risk for effects, such as cancer...

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Bibliographic Details
Main Author: Carlsson, Henrik
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för miljövetenskap och analytisk kemi 2016
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-129248
http://nbn-resolving.de/urn:isbn:978-91-7649-348-9