Dissolving the Rocks : Solubility Enhancement of Active Pharmaceutical Ingredients using Mesoporous Silica

Poor aqueous solubility is one of the greatest barriers for new drug candidates to enter toxicology studies, let alone clinical trials. This thesis focuses on contributing to solving this problem, evaluating the oral toxicity of mesoporous silica particles, and enhancing the apparent solubility and...

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Bibliographic Details
Main Author: Xia, Xin
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för material- och miljökemi (MMK) 2014
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-103190
http://nbn-resolving.de/urn:isbn:978-91-7447-924-9