Dissolving the Rocks : Solubility Enhancement of Active Pharmaceutical Ingredients using Mesoporous Silica
Poor aqueous solubility is one of the greatest barriers for new drug candidates to enter toxicology studies, let alone clinical trials. This thesis focuses on contributing to solving this problem, evaluating the oral toxicity of mesoporous silica particles, and enhancing the apparent solubility and...
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Format: | Doctoral Thesis |
Language: | English |
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Stockholms universitet, Institutionen för material- och miljökemi (MMK)
2014
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-103190 http://nbn-resolving.de/urn:isbn:978-91-7447-924-9 |