Detektion av hydrolyserad β-laktamantibiotika i plasma med Matrix-Assisted Laser Desorption Ionization – Time of Flight Mass Spectrometry och Liquid Chromatography tandem Mass Spectrometry
Introduktion Antibiotikaresistens är ett globalt växande problem. Till gruppen β-laktamantibiotika hör piperacillin-tazobaktam och cefotaxim som båda verkar genom att försvaga cellväggen med kovalenta bindningar till peptidoglykanlagret som lyserar cellen. E. coli och K. pneumoniae tillhör gruppen E...
Main Author: | Thenstedt, Niklas |
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Format: | Others |
Language: | Swedish |
Published: |
Örebro universitet, Institutionen för hälsovetenskaper
2020
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Subjects: | |
Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-84594 |
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