The effect on HbA1c in patients with type 2diabetes who start with FreeStyle Libre– a retrospective study of medical records in Region Örebro County, 2019

• Main Author: Wenell, Lydia
• Format: Others
• Language: English
• Published: Örebro universitet, Institutionen för medicinska vetenskaper 2020
• Subjects: Type 2 diabetes; FreeStyle Libre; HbA1c; hypoglycemia.; Medical and Health Sciences; Medicin och hälsovetenskap
• Online Access: http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-81558

IntroductionFreeStyle Libre (FSL) has mostly been used by patients with type 1 diabetes. In 2019, newrecommendations were announced regarding prescriptions to patients with type 2 diabetes(T2D) who have insulin treatment (basal/bolus), HbA1c > 70 mmol/mol and/or repeatedhypoglycemic events despite great effort to adjust insulin doses.AimTo evaluate if HbA1c improves with FSL compared with self-monitoring of blood glucose. Thesecondary aim was to investigate if patients with recurrent hypoglycemic events experiencedless hypoglycemic events.MethodsThis study was designed as a retrospective systematic review of medical records of patientswith T2D in Region Örebro County (RÖC) who have received an FSL 1st of January to 13th ofSeptember 2019. A control group (n = 142) was created from the National Diabetes Register tothe indication group HbA1c > 70 mmol/mol. A paired sample t-test was used to assess theprimary endpoint.ResultsHbA1c decreased significantly from 73 mmol/mol to 65 mmol/mol (p <0.001) in the wholestudy population (n = 58). Indication group HbA1c > 70 mmol/mol (n = 38) had the greatestchange, 80 mmol/mol to 68 mmol/mol (p <0.001). The mean HbA1c in the control group was82 mol/mol. There were 15 patients in the indication group with hypoglycemic events (n = 20)who experienced less hypoglycemic events.ConclusionFSL has a positive effect on the metabolic control in patients with T2D who have HbA1c > 70mmol/mol when starting with FSL in RÖC.