Post-PKS modifications in the biosynthesis of the antifungal antibiotic nystatin

Post-PKS modifications in the biosynthesis of the antifungal antibiotic nystatin

The antifungal polyene macrolide nystatin is produced by Streptomyces noursei ATCC 11455. The nystatin biosynthesis gene cluster of Streptomyces noursei has been cloned and sequenced, and a biosynthesis route has been predicted. In the present work, investigation of genes presumably involved in post...

Full description

Bibliographic Details
Main Author:	Nedal, Aina
Format:	Doctoral Thesis
Language:	English
Published:	Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi 2007
Online Access:	http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1581 http://nbn-resolving.de/urn:isbn:978-82-471-2971-5

Similar Items

Investigation of the post-polyketide synthase (PKS) modifications during spinosyn A biosynthesis in Saccharopolyspora spinosa
by: Kim, Hak Joong
Published: (2013)

volution of catalase activity during nystatin biosynthesis
by: Cristina Bota, et al.
Published: (2009-03-01)

Comparison the antifungal effect of licorice and nystatin, invitro study
by: Fateme Arbabi-Kalati, et al.
Published: (2013-04-01)

Structural characterization of post-PKS enzymes involved in spinosyn biosynthesis
by: Isiorho, Eta Amauche
Published: (2015)

LIPASE ACTIVITY IN STREPTOMYCES NOURSEI DURING NYSTATIN BIOSYNTHESIS
by: Cristina Bota, et al.
Published: (2008-02-01)

Comparing antifungal effects of Zatariamultiflora and Punicagranatum extract with Nystatin on Candida Albicans
by: F. Nouri, et al.
Published: (2016-12-01)

Comparison of the antifungal effects of various extracts of Onosma Chlorotricum on Candida albicans and Candida glaberata with two antibiotics fluconazole and nystatin
by: Fatemeh Nabipour, et al.
Published: (2018-04-01)

Shared PKS Module in Biosynthesis of Synergistic Laxaphycins
by: Lassi Matti Petteri Heinilä, et al.
Published: (2020-09-01)

Genome mining of novel rubiginones from Streptomyces sp. CB02414 and characterization of the post-PKS modification steps in rubiginone biosynthesis
by: Jingyan Zhang, et al.
Published: (2021-10-01)

Antifungal Activity of Lavandula Angustifolia and Quergues Infectoria Extracts in Comparison with Nystatin on Candida Albicans
by: F. Nouri, et al.
Published: (2016-09-01)

Antifungal Evaluation of Aqueous and Ethanolic Extract of Iranian Dandelion Root, Compared With Fluconazole and Nystatin
by: Alireza Akhzari, et al.
Published: (2021-03-01)

Studies on the Analysis and Mode of Action of Polyene Antibiotics with Particular Reference to Nystatin
by: Cosgrove, R. F.
Published: (1978)

Encapsulation of nystatin in nanoliposomal formulation: characterization, stability study and antifungal activity against Candida albicans
by: Ebrahim Saadat, et al.
Published: (2016-02-01)

Biosynthesis and modification of the antibiotic enduracidin
by: Goebel, Neal C.
Published: (2013)

Comparison of Antifungal Efficacy of Zataria Multiflora and Nystatin for Treatment of Denture Stomatitis: A Randomized Clinical Trial
by: Elnaz Gonoudi, et al.
Published: (2021-03-01)

Sterols in relation to the inhibition of fungi by nystatin /
by: Fowlks, Edison Rudolph
Published: (1965)

Deletion of a Rare Fungal PKS CgPKS11 Promotes Chaetoglobosin A Biosynthesis, Yet Defers the Growth and Development of <i>Chaetomium globosum</i>
by: Biyun Xiang, et al.
Published: (2021-09-01)

Identification of a PKS-NRPS gene involved in the biosynthesis of tenuazonic acid in Alternaria brassicicola
by: Yi-Hsuan, et al.
Published: (2013)

Chemical and biological investigation of iterative PKS-NRPS programming during aspyridone and tenellin biosynthesis
by: Wasil, Zahida
Published: (2014)

In Vitro Assessment of Antileishmanial Activity of Natamycin and Nystatin
by: Arushdeep Sidana, et al.
Published: (2017-05-01)

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.
by: Joleen Masschelein, et al.
Published: (2013-01-01)

Development and validation of an HPLC method for stability evaluation of nystatin
by: Ana Paola Prata Cione, et al.
Published: (2010-06-01)

Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli
by: Sebastian Theobald, et al.
Published: (2019-11-01)

INVESTIGATING KEY POST-PKS ENZYMES FROM GILVOCARCIN BIOSYNTHETIC PATHWAY
by: Tibrewal, Nidhi
Published: (2013)

Vitamin Biosynthesis as an Antifungal Target
by: Zohar Meir, et al.
Published: (2018-06-01)

Lipid Biosynthesis as an Antifungal Target
by: Jiao Pan, et al.
Published: (2018-04-01)

Investigations into the biosynthesis and mode of action of methylenomycin antibiotics from Streptomyces coelicolor
by: Idowu, Gideon Aina
Published: (2017)

Development of a Solid Dispersion of Nystatin with Maltodextrin as a Carrier Agent: Improvements in Antifungal Efficacy against <i>Candida</i> spp. Biofilm Infections
by: Carlos Benavent, et al.
Published: (2021-04-01)

Antifungal activity of punicalagin isolated from Punica granatum and synergism with nystatin against Candida albicans: cellular metabolism, detection of virulence genes and proteomic analysis
by: Silva, Rafaela Alves da
Published: (2018)

Confined Nystatin Polyenes in Nanopore Induce Biologic Ionic Selectivity
by: Khaoula Boukari, et al.
Published: (2016-01-01)

A comparative evaluation of Nystatin, Amphotercin-B and Miconazole in Keratomycosis
by: Reddy P, et al.
Published: (1982-01-01)

The comparison of the effect of curcumin with nystatin on inhibition level of Candida albicans
by: Nosratzehi T, et al.
Published: (2019-08-01)

Formulation and Evaluation of Nystatin Microparticles as a Sustained Release System
by: Sara T.Ismail, et al.
Published: (2017-03-01)

Effect of Thymus vulgaris, Myrtus communis and nystatin on Candida albicans
by: Zia MA, et al.
Published: (2013-11-01)

The effect of Nystatin on the inner ear : an experimental guinea pig study
by: Woods, Owen
Published: (2012)

The effect of Nystatin on the inner ear : an experimental guinea pig study
by: Woods, Owen
Published: (2012)

Coordination of cyclic di-GMP and 4-hydroxybenzoic acid in regulating antifungal antibiotic biosynthesis in Lysobacter enzymogenes
by: Sen Han, et al.
Published: (2020-05-01)

Antifungal Activity of ZnO Nanoparticles and Nystatin and Downregulation of SAP1-3 Genes Expression in Fluconazole-Resistant Candida albicans Isolates from Vulvovaginal Candidiasis
by: Hosseini SS, et al.
Published: (2020-02-01)

Regulation of Lignin Biosynthesis by Post-translational Protein Modifications
by: Daniel B. Sulis, et al.
Published: (2020-07-01)

Genome of Labrenzia sp. PHM005 Reveals a Complete and Active Trans-AT PKS Gene Cluster for the Biosynthesis of Labrenzin
by: Dina Kačar, et al.
Published: (2019-11-01)