Improved determination of genomic uracil content by high performance liquid chromatography-tandem mass spectrometry
Uracil, a nitrogen base usually found in RNA, may be found in small quantities in genomic DNA. Genomic uracil may arise as a result of deamination of cytosine or misincorporation of deoxyuridine monophosphate (dUMP) instead of deoxythymidine monophosphate (dTMP) by replicative polymerases. Uracil is...
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Format: | Others |
Language: | English |
Published: |
Norges teknisk-naturvitenskapelige universitet, Institutt for kreftforskning og molekylær medisin
2011
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-14401 |