Structural studies of Erwinia carotovora L-Asparaginase by X-ray crystallography

Bacterial L-asparaginases (E.C.3.5.1.1) are enzymes that catalyze the hydrolysis of L-asparagine to aspartic acid. For the past 30 years these enzymes have been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia. The presence of a low rate glutaminase activity howe...

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Bibliographic Details
Main Author: Andersson, Charlotta
Format: Others
Language:English
Published: Linköpings universitet, Institutionen för fysik, kemi och biologi 2006
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-6188