Notch signalling in carcinogenesis : With special emphasis on T-cell lymphoma and colorectal cancer
The Notch signalling pathway is an evolutionary conserved pathway, named after the Notch receptors, Notch1-4 in mammals, which upon cell-cell contact and ligand binding releases the intracellular domain (NICD). NICD translocates into the nucleus where it binds the transcriptional repressor RBP-Jk, w...
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| Format: | Others |
| Language: | English |
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Linköpings universitet, Cellbiologi
2009
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51692 http://nbn-resolving.de/urn:isbn:978-91-7393-510-4 |