Thrombin receptor signalling in platelets: PAR1, but not PAR4, is rapidly desensitized

Platelets play a key role in primary haemostasis but are also related to the pathogenesis of arterial thrombosis. Thrombin is the most effective agonist inducing platelet activation. Human platelets express two G-protein coupled thrombin receptors (GPCRs), called protease activated receptor (PAR)1 a...

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Bibliographic Details
Main Author: Haglund, Linda
Format: Others
Language:English
Published: Linköpings universitet, Institutionen för fysik, kemi och biologi 2009
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-18455

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