DNA repair pathways and the effect of radiotherapy in breast cancer

A large proportion of breast cancer patients are treated with radiotherapy. Ionising radiation induces different DNA damages, of which double-strand breaks are the most severe. They are mainly repaired by homologous recombination or non-homologous end-joining. Different protein complexes have centra...

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Bibliographic Details
Main Author: Söderlund Leifler, Karin
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Onkologi 2009
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17955
http://nbn-resolving.de/urn:isbn:978-91-7393-668-2