Unraveling Mechanisms of Insulin Resistance in Type 2 Diabetes in Human Adipocytes : Role of extracellular signal regulated kinase 1/2 (ERK1/2) and forkhead box protein 01 (FOX01)
Type 2 Diabetes is characterized by hyperglycemia primarily caused due to insulin resistance in insulin responsive tissues and insufficient production of insulin by the β-cells. Insulin resistance appears to develop first in the expanding adipose tissue during caloric surplus and affects other tissu...
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Format: | Doctoral Thesis |
Language: | English |
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Linköpings universitet, Avdelningen för cellbiologi
2016
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-131421 http://nbn-resolving.de/urn:isbn:9789176856772 (Print) |