The Akt/mTOR Pathway and Estrogen Receptor Phosphorylations : a crosstalk with potential to predict tamoxifen resistance in breast cancer

Estrogen receptor α content is the primary breast cancer biomarker distinguishing the patients responsive from the non-responsive to endocrine treatments. Tamoxifen is an estrogen competitor with large potential to treat breast cancer patients and prolongs time to recurrence. Despite the estrogen re...

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Bibliographic Details
Main Author: Bostner, Josefine
Format: Doctoral Thesis
Language:English
Published: Linköpings universitet, Avdelningen för kliniska vetenskaper 2013
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-100903
http://nbn-resolving.de/urn:isbn:978-91-7519-515-5 (print)