Supervised Learning for Prediction of Tumour Mutational Burden

Tumour Mutational Burden is a promising biomarker to predict response to immunotherapy. In this thesis, statistical methods of supervised learning were used to predict TMB: GLM, Decision Trees and SVM. Predictions were based on data from targeted DNA sequencing, using variants found in the exonic, i...

Full description

Bibliographic Details
Main Author: Hargell, Joanna
Format: Others
Language:English
Published: KTH, Matematisk statistik 2021
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-291801