p27 and Metastatic Progression: Molecular Mechanisms Underlying Bone Metastasis
The complex PI3K/mTOR pathway regulates tumor progression via effects on cellular proliferation, apoptosis, autophagy, and motility. New drugs that inhibit the catalytic site of both PI3K and mTOR have shown promise in clinical trials. Here, we report the first use of a novel, dual PI3K/mTOR catalyt...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
Scholarly Repository
2011
|
| Subjects: | |
| Online Access: | http://scholarlyrepository.miami.edu/oa_dissertations/690 |