Regulation and action of SKP2 and RhoA in cell and tumor models: Investigation into the molecular mechanisms responsible for the aggressive phenotype of triple-negative breast cancer

Breast cancer tops the list of new cancer cases and is predicted to be the second leading cause of cancer deaths in women in 2012. The primary objective of the present study was to provide insights into the molecular mechanisms underlying the aggressive growth and metastasis of triple-negative and b...

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Bibliographic Details
Main Author: Fagan-Solis, Katerina D
Language:ENG
Published: ScholarWorks@UMass Amherst 2013
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3556243