Allosteric regulation of caspase-6 proteolytic activity

Caspases are cysteine proteases best known for their controlling roles in apoptosis and inflammation. Caspase-6 has recently been shown to play a key role in the cleavage of neurodegenerative substrates that causes Huntington and Alzheimer's Disease, heightening interest in caspase-6 and making...

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Bibliographic Details
Main Author: Velazquez-Delgado, Elih M
Language:ENG
Published: ScholarWorks@UMass Amherst 2012
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3546063