Allosteric regulation of caspase-6 proteolytic activity
Caspases are cysteine proteases best known for their controlling roles in apoptosis and inflammation. Caspase-6 has recently been shown to play a key role in the cleavage of neurodegenerative substrates that causes Huntington and Alzheimer's Disease, heightening interest in caspase-6 and making...
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Language: | ENG |
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ScholarWorks@UMass Amherst
2012
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Online Access: | https://scholarworks.umass.edu/dissertations/AAI3546063 |