The role of human NKG2d receptor-ligand function in tumor immunity and immune escape

NKG2D is a unique immunoreceptor of key significance to immune surveillance of tumor cells, and it represents an attractive candidate in the development of both molecular and cell-based immunotherapies. NKG2D is a stimulatory receptor expressed by human natural killer (NK) cells, cytokine induced ki...

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Bibliographic Details
Main Author: Karimi, Mobin A
Language:ENG
Published: ScholarWorks@UMass Amherst 2012
Subjects:
Online Access:https://scholarworks.umass.edu/dissertations/AAI3545948