The role of inositol 1,4,5 -trisphosphate receptor type-1 in regulation of intracellular calcium oscillations in mouse eggs
Calcium ([Ca2+]i) oscillations, a hallmark of mammalian fertilization, are essential to induce egg activation and embryonic development. As the zygotes transition through the cell cycle, these [Ca 2+]i oscillations progressively diminish until they cease in interphase zygotes. While the mechanism(s)...
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| Language: | ENG |
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ScholarWorks@UMass Amherst
2007
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| Online Access: | https://scholarworks.umass.edu/dissertations/AAI3293932 |