Use of an aggressive, estrogen receptor -negative MCF-7 cell line variant, TMX2 -28, to study breast cancer: Expression of PLD1, MIG2, SKP2, and PALM in human breast carcinomas

Use of an aggressive, estrogen receptor -negative MCF-7 cell line variant, TMX2 -28, to study breast cancer: Expression of PLD1, MIG2, SKP2, and PALM in human breast carcinomas

We have used a novel estrogen receptor-(ER) negative, mixed basal/luminal, aggressive cell line, TMX2-28, as a model to study breast cancer. cDNA microarray comparison of TMX2-28 and its parent non-aggressive, ER-positive cell line, MCF-7, identified 1402 differentially expressed transcripts. Two-hu...

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Bibliographic Details
Main Author: Gozgit, Joseph M
Language:ENG
Published: ScholarWorks@UMass Amherst 2007
Subjects:
Molecular biology
Online Access:https://scholarworks.umass.edu/dissertations/AAI3254930

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