Identificación y caracterización de posibles sitios de desprotonación de sustratos en la enzima monoamino oxidasa A

Identificación y caracterización de posibles sitios de desprotonación de sustratos en la enzima monoamino oxidasa A

Ingeniera Civil en Biotecnología === Ingeniera Civil Química === La enzima Monoamino oxidasa A (MAO-A) participa en las vías de degradación de diferentes neurotransmisores, entre ellos la serotonina, razón por la cual es punto de interés de investigadores para el desarrollo de antidepresivos inhibid...

Full description

Bibliographic Details
Main Author:	Fernández Chicago, Pilar Andrea
Other Authors:	Salgado Herrera, José
Language:	es
Published:	Universidad de Chile 2015
Subjects:	Inhibidores de la monoaminooxidasa Serotonina Reacciones de transferencia protónica MAO-A pKa
Online Access:	http://repositorio.uchile.cl/handle/2250/130661

Similar Items

Aproximación cuántica de cluster para modelar los mecanismos de la Monoamino oxidasa A humana
by: Pérez Comisso, Martín
Published: (2016)

Estudio teórico de fenilisopropilaminas como inhibidores de MAO-A mediante modelación, docking y dinámica molecular
by: Márquez Soto, Daniela Trinidad
Published: (2012)

Potencial inibitório in vitro de biflavonoides de Garcinia gardneriana : um estudo sobre monoamina oxidades e CYP19 (aromatase)
by: Recalde Gil, Maria Angélica
Published: (2016)

Potencial inibitório in vitro de biflavonoides de Garcinia gardneriana : um estudo sobre monoamina oxidades e CYP19 (aromatase)
by: Recalde Gil, Maria Angélica
Published: (2016)

Potencial inibitório in vitro de biflavonoides de Garcinia gardneriana : um estudo sobre monoamina oxidades e CYP19 (aromatase)
by: Recalde Gil, Maria Angélica
Published: (2016)

Study the pKa of C–H Bonds and Proton-Coupled Electron Transfer Process by Transition Metal Complexes via Computational Methods
by: Nazemi, Azadeh
Published: (2020)

Porphyra-334 Isolated from the Marine Algae Bangia atropurpurea: Conformational Performance for Energy Conversion
by: Li-Fan Chuang, et al.
Published: (2014-09-01)

MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY
by: Thiago M. Pereira, et al.

Water-to-air transfer of branched and linear PFOA: Influence of pH, concentration and water type
by: Jana H. Johansson, et al.
Published: (2017-03-01)

Weak acids as an alternative anti-microbial therapy
by: Binu Kundukad, et al.
Published: (2020-12-01)

Revisiting the Kinetics and Mechanism of Bromate-Bromide Reaction
by: Côrtes Carlos Eduardo S., et al.
Published: (2001-01-01)

Systematic Study of the Physicochemical Properties of a Homologous Series of Aminobisphosphonates
by: Jouko Vepsäläinen, et al.
Published: (2012-09-01)

Síntesis de derivados de feniletilamina como potenciales inhibidores de la enzima monoamino-oxidasa (MAO)
by: Gallardo Godoy, Alejandra
Published: (2017)

Síntesis de derivados de feniletilamina como potenciales inhibidores de la enzima monoamino-oxidasa (MAO)
by: Gallardo Godoy, Alejandra
Published: (2012)

Anion–π interactions influence pKa values
by: Christopher J. Cadman, et al.
Published: (2011-03-01)

Asetonitril-Su İkili Karışımlarında Piroksikam ve Tenoksikam'ın Potansiyometrik pKa Tayini
by: Ebru Çubuk Demiralay, et al.
Published: (2012-06-01)

Outline of an experimental design aimed to detect protein A mirror image in solution
by: Osvaldo A. Martin, et al.
Published: (2019-10-01)

Deprotonation of salicylic acid and 5-nitrosalicylic acid in aqueous solutions of ethanol
by: Faraji Mohammad, et al.
Published: (2011-01-01)

Determinação espectrofotométrica do pKa e desenvolvimento de dispersões sólidas da nova entidade química LPSF/FZ4: um promissor agente esquistossomicida
by: Medeiros, Giovanna Christinne Rocha de
Published: (2015)

Enhancing Carbon Acid pK<sub>a</sub> Prediction by Augmentation of Sparse Experimental Datasets with Accurate AIBL (QM) Derived Values
by: Jeffrey Plante, et al.
Published: (2021-02-01)

cis–trans-Amide isomerism of the 3,4-dehydroproline residue, the ‘unpuckered’ proline
by: Vladimir Kubyshkin, et al.
Published: (2016-03-01)

Calculation of the Global and Local Conceptual DFT Indices for the Prediction of the Chemical Reactivity Properties of Papuamides A–F Marine Drugs
by: Norma Flores-Holguín, et al.
Published: (2019-09-01)

Theoretical calculations of the relative pKa values of some selected aromatic arsonic acids in water using density functional theory
by: Behzad Khalili, et al.
Published: (2016-01-01)

Calculation of VS,max and Its Use as a Descriptor for the Theoretical Calculation of pKa Values for Carboxylic Acids
by: Guillermo Caballero-García, et al.
Published: (2018-12-01)

An Experimental Validated Computational Method for pKa Determination of Substituted 1,2-Dihydroxybenzenes
by: Romina Romero, et al.
Published: (2018-07-01)

DETERMINATION AND EVALUATION OF ACIDITY CONSTANTS OF SOME IMIDAZOLE AND THIAZOLE LINKED ACETAMIDE COMPOUNDS
by: Funda Tay, et al.
Published: (2016-07-01)

Prediction of pKa values using the PM6 semiempirical method
by: Jimmy C. Kromann, et al.
Published: (2016-08-01)

Synthesis of δ-Oxo-1,1-bis(triflyl)alkanes and Their Acidities
by: Hikaru Yanai, et al.
Published: (2013-12-01)

Theoretical considerations regarding the thione-thiol tautomerism in 2-(5-mercapto-1,3,4-thiadiazol-2-ylthio)acetic acid
by: Raluca Oana Pop, et al.
Published: (2015-02-01)

Coulometric–potentiometric determination of pKA of several organic bases in propylene carbonate
by: LJILJANA N. JAKSIC, et al.
Published: (2008-06-01)

Determinação das constantes de dissociação protônica do 2,7- naftalenodiol no primeiro estado excitado singlete por experimentos com resolução temporal e modelagem matemática = Determination of protonic dissociation constants of 2.7- naphthalenediol in the first excited singlet state by experiments with temporal resolution and mathematical modeling
by: Ira Mark Brinn, et al.
Published: (2006-01-01)

Comparison of zwitterionic N-alkylaminomethanesulfonic acids to related compounds in the Good buffer series
by: Robert D. Long, et al.
Published: (2010-04-01)

Studies On Some Acid Divalent-Metal Nitrilotriacetate Complexes
by: N. E. Milad, et al.
Published: (2000-10-01)

The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
by: Lasse I. Blaabjerg, et al.
Published: (2018-09-01)

Aplicação da equação de Poisson-Boltzmann ao cálculo de propriedades dependentes do pH em proteínas Aplications of the Poisson-Boltzmann equation to the calculation of pH-dependent properties in proteins
by: Thereza A. Soares, et al.
Published: (2004-08-01)

Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation
by: Surash Ramanathan, et al.
Published: (2015-03-01)

Apparent monomer activity of saturated fatty acids in micellar bile salt solutions measured by a polyethylene partitioning system
by: Verney L. Sallee
Published: (1974-01-01)

Raman spectroscopic studies of the hepatitis delta virus (HDV) ribozyme
by: Gong, Bo
Published: (2009)

Theoretical Estimation of pKa’s of Pyrimidines and Related Heterocycles
by: Wessner, Rachael Ann
Published: (2016)

Theoretical investigation of cyclooxygenase inhibition property of several non-steroidal anti-inflammatory drugs by density functional theory calculations and molecular docking studies
by: Atena Najdian, et al.
Published: (2015-12-01)