Selective neurodegeneration in Alzheimer's disease and Parkinson's disease
Alzheimer’s disease (AD) and Parkinson’s disease (PD) are featured by cholinergic and dopaminergic neuron loss, respectively. As a unique pathological hallmark of AD, neuritic plaques contain aggregated amyloid β protein (Aβ), generated from amyloid β precursor protein (APP). APP mutations cause fam...
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Language: | English |
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University of British Columbia
2017
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Online Access: | http://hdl.handle.net/2429/63267 |