Using pathogen inactivation treatment to study the stability of platelet messenger RNA

Pathogen inactivation (PI) techniques are designed to increase the safety of blood products by damaging RNA and DNA of pathogens. Even though platelets are anucleate, they synthesize proteins using RNA and the ribosomal machinery derived from megakaryocytes. The role of protein synthesis in platelet...

Full description

Bibliographic Details
Main Author: Klein-Bosgoed, Christa
Language:English
Published: University of British Columbia 2017
Online Access:http://hdl.handle.net/2429/61783