Overexpression of human processing alpha-glucosidase I and functional study of yeast processing alpha-glucosidase I

Processing α-glucosidase I (Glu I) holds a key regulatory position in the N-glycosylation pathway. Glu I mutations in humans have severe or fatal outcomes. Despite the important role of human Glu I (MOGS), very little information is available regarding the function, mechanism and structure of the en...

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Bibliographic Details
Main Author: Peng, Zhong
Language:English
Published: University of British Columbia 2016
Online Access:http://hdl.handle.net/2429/59087