Binding of substrates and inhibitors to human pancreatic alpha amylase
Human pancreatic alpha-amylase (HPA) is the enzyme responsible for hydrolyzing starch within the gut into shorter oligosaccharides. Selective inhibition targeted at only HPA could be used to modulate blood glucose levels for the treatment of diabetes and obesity. Montbretin A (MbA) is a potent (Ki...
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| Language: | English |
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University of British Columbia
2016
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| Online Access: | http://hdl.handle.net/2429/58311 |